Hall of Fame

Winner Fall 2020 Challenge
Benjamin Strickland
Drew University
Madison, United States

In Silico Discovery of Potent Novel Antibacterial Lead Compounds Inhibiting FtsZ

Pathogenic bacteria resistant to current first-line antibiotic treatments in the United States are responsible for two million infections a year, placing a strain upon the United States healthcare system and increasing expenditure by an estimated $20 billion per year in associated medical costs. Of particular concern is the pathogenic bacterium methicillin-resistant Staphylococcus aureus (MRSA), which exhibits resistance towards almost all clinical β-lactams (e.g. penicillins, cephalosporins, and carbapenems). MRSA commonly acquires additional resistance determinants, giving rise to multidrug-resistant MRSA subtypes (MDRSA) which can be especially challenging to treat. The bacterial cellular division protein Filamenting temperature-sensitive mutant Z (FtsZ) represents a novel...
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Winner Summer 2020

Javier García Marín

Centro de Investigaciones Biológicas Margarita Salas
Madrid, Spain
Computational Approaches to Block SARS-CoV-2 Entry
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Winner Spring 2020

Antonio Colom

Inter American University Metro Campus
San Juan, United States
Computational docking experiments of a novel S. aureus gyrase inhibitor
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Winner Winter 2019

Azhar Salari-jazi

Isfahan University of Medical Science
Isfahan, Iran
Inhibition of efflux pumps in Gram-negative bacteria by small molecule design
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Winner Fall 2019

Surid Mohammad Chowdhury

Southeast University
Dhaka, Bangladesh
In silico design of novel benzodiazepines as potent sedative-hypnotics
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Winner Summer 2019

Jessica Holien

St. Vincent's Institute of Medical Research
Fitzroy, Australia
Structure-based drug design of selective Drp1 inhibitors for dementia treatment
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Winner Spring 2019

Sandesh Neupane

University of Strasbourg
Identification of potential drugs for brain tumour using integrated approaches
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Winner Winter 2018

Daniela Dolciami

University of Perugia
Perugia, Italy
Immune-mediated diseases treatment by selective Aryl hydrocarbon Receptor modulators
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Winner Fall 2018

Vinicius Barros Ribeiro Da Silva

Université Grenoble Alpes
Grenoble, France
Chemical Rationalization of Bacterial Efflux Pump Substrates
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Winner Summer 2018

Ivana Šagud

Faculty of Chemical Engineering and Technology
Zagreb, Croatia
Novel potent oxazole containing cholinesterase inhibitors
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Winner Spring 2018

Sharat Chandra

Center for Translational Pain Medicine, Department of Anesthesiology, Duke University
Durham, United States
Identification of selective non-opioid small molecule analgesics by targeting Nav1.7
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Winner Winter 2017

Javier García Marín

Universidad de Alcalá
Alcalá de Henares, Spain
Computer-Aided Identification of New Disrupting Molecules of ILK-Parvin Interaction
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Winner Fall 2017

Nadezhda Demina

Ural Federal University
Ekaterinburg, Russia
Dual action agent: activator of glucokinase and inhibitor of dipeptidyl peptidase-4
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Winner Summer 2017

Julius Pollinger

Frankfurt am Main, Germany
Computer-assisted selective optimization of side-activities
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Winner Winter 2016

Marko Jukič

Department of Medicinal Chemistry, Faculty of Pharmacy, Universiy of Ljubljana
Ljubljana, Slovenia
Small-molecule glycosyltransferase (GTs) inhibitors based on pyranose monosaccharides
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Winner Spring 2017

Veera Chandra Sekhar Reddy Chittepu

Escuela Nacional de Ciencias Biológicas, Instituto Politecnico Nacional
Mexico City, Mexico
Epigenetics Drug Discovery of natural product libraries to be anticancer/antidiabetic
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Winner Fall 2016

Sophia Borisevich

Ufa Institute of Chemistry
Ufa, Russia
Drug-Design of 3-Amino Derivatives of (-)-Cytisine- Potential Inhibitors of COX-2
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Winner Summer 2016

Reinaldo Fraga

Cuban Research Institute on Sugarcane By-Products (ICIDCA)
Havana, Cuba
Inhibitors of dextransucrase enzymes and the decrease of dextran content in the sugar
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Winner Spring 2016

Dr. Subhash Mohan Agarwal And Dr Prajwal Nandekar .

Heidelberg Institute for Theoretical Studies (PN), Germany AND Institute of Cytology and Preventive Oncology (SMA)
Noida, India
Reversible inhibitors against drug resistant Epidermal Growth Factor Receptor (EGFR) mutant
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Winner Winter 2015

Maria Letizia Barreca

University of Perugia
Perugia, Italy
Identification of pharmacological chaperones for cellular prion protein
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