SeeSAR is your intuitive, visual drug design platform. Covering every step of your drug discovery process —
from virtual screening to fragment-based design — SeeSAR fosters ideation in the most fun and comprehensive way.
infiniSee is your Chemical Space navigation platform. Based on similarity, infiniSee finds molecules of interest in
screening libraries or Chemical Spaces of almost infinite size. Given a template or query molecule, infiniSee
returns unexpectedly similar molecules.
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors playing a critical role in the regulation of metabolic homeostasis, and thus represent valuable therapeutic targets for the treatment of metabolic disorders. The PPAR family comprises three different subtypes: α, β/δ, and γ, whose expression and actions differ according to subtype, organ, and tissue cell type. The development of more balanced drugs interacting with PPARs, devoid of the side-effects showed by some marketed agonists, is considered a major challenge. We recently reported a novel PPAR pan-agonist, AL29-26, with an attractive and balanced activity profile, which represents an interesting lead of a new...