SeeSAR is your intuitive, visual drug design platform. Covering every step of your drug discovery process —
from virtual screening to fragment-based design — SeeSAR fosters ideation in the most fun and comprehensive way.
infiniSee is your Chemical Space navigation platform. Based on similarity, infiniSee finds molecules of interest in
screening libraries or Chemical Spaces of almost infinite size. Given a template or query molecule, infiniSee
returns unexpectedly similar molecules.
Pathogenic bacteria resistant to current first-line antibiotic treatments in the United States are responsible for two million infections a year, placing a strain upon the United States healthcare system and increasing expenditure by an estimated $20 billion per year in associated medical costs. Of particular concern is the pathogenic bacterium methicillin-resistant Staphylococcus aureus (MRSA), which exhibits resistance towards almost all clinical β-lactams (e.g. penicillins, cephalosporins, and carbapenems). MRSA commonly acquires additional resistance determinants, giving rise to multidrug-resistant MRSA subtypes (MDRSA) which can be especially challenging to treat. The bacterial cellular division protein Filamenting temperature-sensitive mutant Z (FtsZ) represents a novel...