SeeSAR is your intuitive, visual drug design platform. Covering every step of your drug discovery process — from virtual screening to fragment-based design — SeeSAR fosters ideation in the most fun and comprehensive way.
ExploreinfiniSee is your Chemical Space navigation platform. Based on similarity, infiniSee finds molecules of interest in screening libraries or Chemical Spaces of almost infinite size. Given a template or query molecule, infiniSee returns unexpectedly similar molecules.
Set sailCovalent docking, is one of the main innovations of the upcoming SeeSAR 11 release called ‘Hephaestus’, inspired by the Greek god of craftsmen, artisans, forgery, and vulcanoes. Covalent ligands bear a functional group or motif in their molecular structure, the so-called ‘warhead’, which interacts with an nucleophile side chain (e.g....
Read onAminergic GPCRs are considered as clinically validated drug targets in multiple psychiatric indications. György contributed to the discovery of the third generation antipsychotic drug cariprazine (Vraylar®/Reagila®) targeting these receptors. Now, detailed mechanism of action studies revealed further exciting findings. Up to now, the functional activity of GPCR ligands has traditionally...
Read onIn modern drug discovery, speed is trumps because time is money. Virtual screening methods bring those benefits to the table that ring a bell for any project leader: They are cheap and fast. In the past, several FDA-approved drugs emerged from computer-aided structure-based drug discovery. Among the used methods, molecular...
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