Adverse drug reactions (ADRs) are not only a significant concern in public health but also one of the main challenges in drug discovery. This is especially true for anti-cancer drug development, which is slow and costly; ADRs can also be the cause of drug withdrawals from the market. The interactions of anti-cancer drugs at off-target sites in the body may result in a wide range of undesired effects that occur through complex biological mechanisms and may turn out severe enough so that they result in hospital admissions. A suitable drug delivery system cannot only improve the effectiveness of a drug but also serve to reduce its adverse reactions.
In this BioSolveIT Webinar, Laleh will discuss case studies, where the application of computational simulations has aided. This covers the analysis of a drug mechanism of action at potential off-target sites, or designing and evaluating specific drug delivery systems to mitigate the unwanted impact of chemotherapeutic agents.
Join us for an interesting twist on computational drug discovery methods and vivid discussions!