PepSee is a software tool for interactive, visual compound prioritization as well as the design of next-generation peptide therapeutics. Peptide design ideally supports a multi-parameter optimization to maximize the likelihood of success. PepSee visualizes the relevant parameters at hand, side by side with the sequence data. Color-coded display stimulates SAR exploration.
The main features of PepSee comprise:
The vast majority of peptide analytics and design today is done in Excel. But as soon as the length and number of sequences grows and more and more data accumulates, Excel is not adequate anymore. Here is a comparison:
|assembling tabular data|
|easily focus on the rows and columns of interest|
|live data plots|
|compounds organized in groups|
|automated alignments that can still manually be tweaked|
|highlighting/filtering based on sequence motifs|
|various color-coding options for the sequence data|
Dr. Torsten Hoffmann, COO Silence Therapeutics, former CSO Zealand Pharma and CSO Proteros biostructures
PepSee is filling an enormous gap in peptide therapeutics analysis and design.
Dr. Frosty Loechel, Evotec
I was doubtful in the beginning — but you guys really delivered with PepSee.
Keld Fosgerau, PhD, CSO, Gubra aps
It was a great pleasure to have contributed to this creative project with you guys.
Jan Holst Jensen, PhD, CEO and Founder of BiochemFusion
A sheer pleasure! — And PepSee works beautifully with our database tools.
Marie Skovgaard, PhD, Director Medicinal Chemistry at Zealand Pharma A/S
In retrospect working with Excel now seems like living in the stone age.
Jakob Lind Tolborg, Consultant
Spotting relations between sequence patterns and assay data is a central challenge in peptide drug discovery. In the past scientists had only Excel to do this, but with PepSee, looking back at Excel now feels like black and white TV.
I want to import my data to see sequence and properties of interest side by side.
I want to understand the SAR, so show me where changes result in a certain effect!
In order to see commonalities/differences I need to align my sequences.
For my peer group I need an easy way to present my data.
Commercial customers: please request a free trial license here!
PepSee is by design easy to use and pretty self-explanatory. Still, in order to give you a jump-start, we have prepared for you a tutorial-style guide through it's various functionalities. as well as an
To import your data from Excel, please use the same format as is in this sample data file. For an introduction of PepSee and various show cases we recommend you to take a look at this
In publications please cite PepSee with the respective version number as follows: