The latest update of Enamine’s REAL Space brings a new expansion, now featuring over 94.5 billion accessible, drug-like products, approaching the 100 billion mark. Built from 173 curated reaction protocols and 202,620 in-stock reagents and building blocks based on Enamine’s in-house knowledge, this version further enhances the world’s largest commercially available compound collection designed for drug discovery.
Every compound in REAL Space is assembled via well-validated parallel synthesis protocols applied to qualified in-stock reagents at Enamine. This ensures that all virtual products reflect real, performable chemistry, with a synthesis success rate of over 80% and delivery in 3–4 weeks.
Key Traits
- Make-on-demand: synthesized to order and delivered to your lab
- Drug-like physicochemical properties (Ro5 and Veber compliant)
- Verified synthetic accessibility via validated parallel synthesis protocols
- Fast delivery: 3–4 weeks with over 80% synthesis success rate
The REAL Space update is available to download and can be screened with BioSolveIT applications:
- infiniSee
- Chemical Space Docking®
- FTrees (fuzzy pharmacophore search)
- SpaceLight (fingerprint/Tanimoto similarity)
- SpaceMACS (substructure matching)
All results found using BioSolveIT software are ready to order directly from Enamine, ensuring a streamlined path from virtual screening to your laboratory.