DrugSpace Symposium 2025

Interdisciplinary Approaches for Novel Drug Candidates

As drug discovery continues to evolve at a rapid pace, collaboration and innovation across disciplines are more important than ever.
Therefore, we are excited to host the fourth BioSolveIT DrugSpace Symposium. The 2025 edition will focus on interdisciplinary interfaces between medicinal and computational chemistry, along with all related methods.
Taking the big picture into account, we are especially proud to welcome experts from both industry and academia, who will present and discuss their most recent research.

The fourth DrugSpace Symposium will take place on September 24–25, 2025.
Sessions are scheduled to begin each day at 3:00 PM (Berlin time, GMT+2).
As the Symposium Finale, we conclude the sessions with a BioSolveIT Day, taking place on September 26, 2025, starting at 3:45 PM (Berlin time, GMT+2).

Secure your free spot at the DrugSpace 2025 Symposium:

Programme

DrugSpace Symposium 2025
Time (CEST)	September 24	September 25
2:45 – 3:00 pm	Welcome Address	Welcome Address
3:00 – 3:45 pm	Jens Carlsson University of Uppsala Structure-based Virtual Screening for Enzyme Inhibitors in Vast Chemical Space	Abdurrahman Olğaç Gazi University Integrative Computational Approaches for Multi-Target Drug Discovery in the Arachidonic Acid Pathway
3:45 – 4:30 pm	Pierre Llompart Sanofi Harnessing Medicinal Chemical Intuition from Collective Intelligence	Tuomo Kalliokoski Orion Pharma SpaceHASTEN: Keep on Dockin’ in the Nonenumerated World
4:30 – 5:15 pm	Christoph Grathwol University of Karlsruhe Collaborative Impact of Academic Compound Management on Biological Screening	Andrea Volkamer HIPS Saarland (Institute for Pharmaceutical Research) Efficient Exploration of Kinase Inhibitor Space: A Fragment-Based and Subpocket-Guided Approach
5:15 – 6:00 pm	Zuzanna Kozicka Harvard Medical School Molecular Glue Degraders: Fantastic Drugs and Where to Find Them	Letizia Barreca University of Perugia Folding-Interfering Small Molecules: Pioneering Innovation Beyond Classical Drug Design
6:00 – 6:45 pm	Michael Ashley Spies University of Iowa Large Curated Chemical Spaces and the Race toward Species Specific Therapeutics to Treat H. Pylori Infections	Alexey Zakharov NIH (National Institutes of Health) AI-Driven Drug Discovery: Bridging Medicinal Chemistry and Machine Learning
6:45 – 7:30 pm	Frédéric Dreyer Exscientia, Genentech Assessing Interaction Recovery of Predicted Protein-Ligand Poses	Allison Mason AbbVie Advancing Chemical Spaces: Enhancing Product Properties with AbbVie’s Monomer Quality Score
7:30 – 8:15 pm	Laurie Christianson FMC Corporation Finding Novel Actives Using Rare Fragments from Bayesian Models

Bonus Programme September 26 — BioSolveIT Day

BioSolveIT Day 2025
Time (CEST)	September 26
3:45 – 4:00 pm	Welcome Address
4:00 – 4:45 pm	Introduction to SeeSAR and infiniSee Spotlight on BioSolveIT’s Product Portfolio: Computational Tools for Drug Discovery Campaigns
4:45 – 5:30 pm	Combinatorial Chemical Spaces vs. Enumerated Compound Libraries Benchmarking Commercial Compound Sources with a Novel Set of Bioactive Molecules
5:30 – 6:15 pm	Next Generation of Virtual Screening: Chemical Space Docking® Structure-based Exploration of Trillion+-sized Compound Collections
6:15 – 6:45 pm	Creating Your Own Chemical Space: First Steps towards a Successful Future How to Assemble Your Own Ultra-Large Set of Synthesizable Compounds — Accompanied by Decision-ready Insights

Inviting All Drug Discovery Enthusiasts

The BioSolveIT DrugSpaces Symposium aims to be accessible to the global drug discovery and chemistry research community.
In order to do so, the whole event is free-of-charge and everybody is cordially invited to participate. This includes Medchems and Compchems, decision-makers, professionals from the pharmaceutical, crop science, and healthcare sectors, as well as undergraduate and PhD students, and researchers in general.

Most importantly, we extend our sincere thanks in advance to all brilliant speakers and participants for their valuable contributions.

Bridging Science: Connecting the Pieces to Drug Discovery

During DrugSpace 2025, drug discovery will be explored from a wide range of perspectives.
We are honored to host top experts who will share the most recent insights into medicinal and computational chemistry.

During the medchem sessions, we will delve into key areas of small molecule discovery, scaffold extension and manipulation, and state-of-the-art lead optimization. Beyond classical structure-based design campaigns, exciting topics such as targeting protein intermediates and molecular glues will also be addressed.

The compchem talks will cover topics such as the screening of ultra-large compound collections, along with the opportunities they offer and the challenges they present. The cornerstone of structure and binding mode prediction will be examined from multiple perspectives, including its application in various workflows.

No drug discovery symposium would be complete without an update on the latest developments in AI methods and their applications. These sessions will also touch on the growing role of big data processing in accelerating research and decision-making across the field.

In summary, DrugSpace 2025 brings together diverse approaches, disciplines, and innovations, bridging science across domains, scales, and mindsets.

BioSolveIT Day 2025 — Finale to the DrugSpace Symposium

DrugSpace 2025 wraps up with a deep dive into BioSolveIT’s newest developments. On September 26, you will get a behind-the-scenes look at our tools in action, from everyday design workflows to trillion-scale Chemical Space Docking®. We’ll also unpack our latest open-access paper comparing combinatorial Chemical Spaces with enumerated libraries—who really performs better? Expect concise talks, interactive demos, and practical takeaways you can implement into your drug discovery campaigns.

Please register via the DrugSpace Symposium page; BioSolveIT Day is also free of charge.

Valuable Disclaimer

Due to frequent requests in recent editions and due to the length of the symposium, we are offering participants the option to receive a certificate of attendance this year.
So if you need a certificate because you would like to count the symposium as working hours or professional training, or if you need it for your graduate school, that’s no problem.