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REAL Space Navigator

explore the REAL Space
... to boldly go where no chemist has gone before

what it does

REAL Space Navigator is the world's largest, ultra-fast searchable chemical space developed in collaboration with Enamine Ltd. It comprises roughly 13 billion compounds today, which will be delivered on demand in less than 4 weeks with an exceptional success rate of 80% and above. This vast resource allows for efficient hit exploration, from finding previously unknown analogues to scaffold hopping. The chemical space is based on 183 Enamine synthesis protocols and in-stock building blocks. It provides an escape from availability bias of current stock screening collections towards IP free areas. The average search time in this space is between 2 and 4 minutes on a standard PC. Simply download → install & execute to explore more than thirteen billion molecules within less than 5 minutes.


read the flyer
  • yes, the space is virtual but all compounds in it are available on demand
  • secure search: REAL Space Navigator runs behind your firewall
  • delivered time: less than 4 weeks, success rate: 80% and above
  • search time: 2 to 4 minutes on average for a typical lead
  • exceptional scaffold hopping capabilities allow you to explore IP free areas


Download REAL Space Navigator for your platform (Note that at least 4GB of main memory are required):

REAL Space Navigator is equipped with a free license for 3 days after the download, allowing you to locate any molecules of interest and place an order. If you are interested in a longer term license, this is available for a fee. Please contact us for a quote.


REAL Space Navigator is super-easy to use. Yet, just in case, here is a little bit of help, as well as an introductory deck of slides and a recent ...

... webinar recording

citing toolname

In publications please cite REAL Space Navigator with the respective version number as follows:

REAL Space Navigator version 4.0; BioSolveIT GmbH, Sankt Augustin, Germany, 2020,


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