Summer Workshop: Fragment-based Compound Evolution

webinar

Wed, 21 Jul 2021, 16:00 CEST (Berlin)

Alexander Neumann, BioSolveIT

Summer Workshop: Fragment-based Compound Evolution

Fragment-based drug design (FBDD) receives more and more attention in the scientific community. The the fifth fragment-derived drug, sotorasib, received approval by the FDA for the treatment of non-small cell lung cancer this year. In this workshop we will discuss strategies around FBDD with recent med-chem use cases and how to utilize resources for lead optimization and idea generation. by thinking outside the box. Learn how to evolve a weak binder to a full-fledged drug candidate.

Participants can request a certificate of attendance.

Current news

Freedom Space by Chemspace March 2026 Update - Now a MASSIVE 296 Billion!
March 5, 2026 10:09 CET
The March 2026 update of Freedom Space brings a significant expansion, now featuring over 296 billion accessible, drug-like products. Created by Chemspace, this collection was built from 39 reaction protocols and 215,000 reagents sourced from 15 of the most reliable suppliers. By prioritizing price and lead time, this version enhances...
Read on
category
Events
Tool of the Month - SpaceMACS
February 26, 2026 14:08 CET
Spotlight on SpaceMACS: Precision Substructure Mining at Scale In the search for the next lead candidate, medicinal chemists often focus on specific structural motifs while requiring absolute synthetic accessibility. This month, we focus on SpaceMACS, our specialized algorithm designed to perform rapid substructure searches across trillions of compounds within massive...
Read on
Introducing SAVI Space - Taking the Step After Enumeration with the SAVI Space
February 25, 2026 11:28 CET
The SAVI Space (short for Synthetically Accessible Virtual Inventory) is a combinatorial Chemical Space designed for ultra-large scale virtual screening. Developed by the U.S. National Institutes of Health (NIH) and transformed by researchers at the University of Hamburg (ZBH), it marks a technical shift from static molecular libraries to dynamic,...
Read on