The March 2026 update of Freedom Space brings a significant expansion, now featuring over 296 billion accessible, drug-like products. Created by Chemspace, this collection was built from 39 reaction protocols and 215,000 reagents sourced from 15 of the most reliable suppliers. By prioritizing price and lead time, this version enhances one of the largest and most diverse collections available for computational drug discovery.
Chemspace utilizes custom SMARTS patterns to preselect building blocks, followed by innovative machine learning based (ML-based) filters to refine reagent pools. This rigorous approach ensures high-quality synthons and a synthesis success rate of over 80%.
Key Traits
- Innovative ML-based filtering of building blocks
- High chemical diversity across an ultra-large space
- Verified synthetic accessibility
- Fast delivery to your laboratory
The Freedom Space update is available to download and can be screened with BioSolveIT applications:
- infiniSee
- Chemical Space Docking®
- FTrees (fuzzy pharmacophore search)
- SpaceLight (fingerprint/Tanimoto similarity)
- SpaceMACS (substructure matching)
All results found using BioSolveIT software are ready to be synthesized and ordered via the respective suppliers, ensuring a streamlined path from virtual screening to your laboratory.