Dear Drug Discovery Enthusiast,

We thought this might be interesting for you:

Symposium "DrugSpace — Targets, Compounds, Spaces"

In the first virtual BioSolveIT symposium, experts discuss current developments and unprecedented innovations to tackle future challenges in drug discovery.
The symposium features interdisciplinary cross-talks on protein structures, crystallography, synthetic accessibility, small-compound evolution, and methods how to navigate colossal Chemical Spaces. Save the date: 21-22 April 2021.
Researchers, representatives of academia and industry, students, and all enthusiasts are cordially invited to participate.

Free Webinar: How To Design Selective Ligands for Highly Conserved Binding Sites

A major goal of drug design projects is to obtain high affinity ligands for a certain target while maintaining selectivity over potential off-targets and thereby reducing side effects. That, however, proves to be challenging when facing a highly conserved binding site. Using the N-myristoyltransferase of Leishmania major and the human homolog as a model system, the molecular selectivity-determining features for different inhibitors were identified by computational and experimental methods. By understanding these features, novel selective inhibitors were identified. Guidelines when facing conserved binding sites are presented, and Christian is available for discussion after his presentation.

Deadline Scientific Challenge approaching

Both academic and independent researchers are encouraged to submit their drug discovery proposal for our Spring 2021 Scientific Challenge until Sunday, February 21st. The best 5 proposals get free access to BioSolveIT's finest software to support them in their project in the right direction: molecular modeling, screening, scaffold replacement, similarity searching, de novo design, KNIME workflows.
The deadline is approaching fast, so check out the details here.

Hope to (virtually) see you soon!

        Your BioSolve-rs